Courtesy Honor Fraser Gallery & Portland Art Museum
Art and drugs have a history that stretches back millennia. But when it comes to modern and contemporary approaches, science, technology and concept have broadened the horizons for artists making drugs their subject. Scroll through the gallery to discover some of the most beautiful and notorious works influenced by the world of narcotics.

Pictured: "Cosmic Cavern" (2015) by Kenny Scharf.
Courtesy Honor Fraser Gallery & Portland Art Museum
Pop surrealist Kenny Scharf built the first of his "Closets" in New York, 1981 in a loft he shared with Keith Haring. "I made it as a place to go and trip," he explains, recalling a period "when I was really into mushrooms -- doing them maybe once a week." Scharf's "safe space" evolved, becoming a cathedral of Day-Glo bricolage, with over 30 iterations in four decades, from LA to Tokyo. His latest offerings, the Cosmic Cavern at the Portland Art Museum and the Nassau County Museum of Art, show Scharf's desire to cram as much psychedelic goodness into one space as possible is anything but diminished.
courtesy Diddo
"Ecce Animal" by Dutch artist Diddo is not your usual skull. Sculpted from gelatine and compressed cocaine, the powder was all sourced from the street and rigorously tested in a lab for its purity -- only around 15-20% once 'cutting agents' including caffeine and paracetamol were accounted for. The sculpture is a Yorick for Generation X, but not, explains the artist, preoccupied with mortality, nor "intended to be parable on the self-destructiveness of addiction or substance abuse." He says the piece meditates upon the conflict between our civilized societies and the vestiges of our animal instincts. "Cocaine helps relieve the tension between the conflicting forces," Diddo argues. "It complements the intended message."
GABRIEL BOUYS/AFP/AFP/Getty Images
Britart enfant terrible Hirst has previously stated how his voracious appetite for drugs and alcohol turned him into a "babbling wreck" for a period. Now teetotal, drugs have as been as much of a subject as a stimulant for the artist. Hirst submitted twelve cabinets stacked with containers of medication as part of his thesis at Goldsmith's College of Art, London in 1989, and expanded with "Pharmacy" in 1992, an installation featuring cabinets stacked with pharmaceutical drugs and all the furnishings of a laboratory or hospital. By 2000 the packaging had gone, and with "Standing Alone on the Precipice and Overlooking the Arctic Wastelands of Pure Terror" he presented thousands of resin and plaster "pills". Shown at the Venice Biennale in 2003, Hirst's critics have interpreted the work as a response to Max Beckermann's suggestion that painting -- and perhaps more widely art -- helps in dealing with the "void" of acknowledging our mortality.
Sarah Schoenfeld
For her series "All You Can Feel", Berliner Sarah Schoenfeld bought drugs both legal and illegal and dissolved them in water and alcohol, dropping the chemical solutions on to exposed 35mm film. The result is the beautiful corrosion of the negative in myriad colors and compositions. "The photographic negative is built of four different layers, which are on top of each other," the artist told CNN. "Normally the light waves would touch one of the layers according to their wavelength and 'print' their image on this layer." She describes her method as a different kind of exposure. "If you compare this to taking drugs, you would also eventually 'see' things, which are not caused by light and wavelength of the outer world, but by chemical processes inside your brain and body."
Bryan Lewis Saunders
Tennessee-based artist Bryan Lewis Saunders has created a self-portrait every day since January 30, 1995, but is perhaps best known for his series "Under the Influence", a series of self-portraits created while under the effects of a variety of drugs.
Bryan Lewis Saunders
Saunders never paid for any of the substances -- as wide-ranging as heroin, bath salts and Xanax -- during the course of the series of over 100 self-portraits. In retrospect the artist calls the experiment "self-abuse," saying "I wasn't in the best of places mentally." What's striking about the series is the sheer variety of styles induced by intoxicating experiences. Saunders says in summary that drugs make you look ugly in art, and that "it's very easy to sensationalize it."
NELSON ALMEIDA/AFP/AFP/Getty Images
Before Abramović's magnus opus "Rhythm 0" came "Rhythm 2", a two-part performance piece inspired by her loss of consciousness during "Rhythm 5". Performed at the Gallery of Contemporary Art, Zagreb, the first half of the performance saw Abramović take a drug prescribed for people with catatonia. As a healthy person not afflicted with the muscle immobilizing condition, the artist lost control of her body over 50 minutes, experienced violent spasms while remaining perfectly lucid. When the first drug wore off Abramović ingested a different medication, this time intended for people exhibiting violent, schizophrenic behavior. This time her body remained in control, but the artist became mentally detached from her environment, "forgetting who and where I am," she recalls.
KENA BETANCUR/AFP/AFP/Getty Images
Warhol protégé Jean-Michel Basquiat died of a heroin overdose aged 27 in 1988, leaving behind a remarkable collection of neo-expressionist art. Basquiat, a friend of Keith Haring, is extremely popular in today's contemporary art market, with "Untitled" (pictured) selling for $57.3 million in May 2016. His former girlfriend in an interview with the BBC in 2010 suggests his art reflects the type of drugs he was using at the time: "little tiny detailed paintings" indicative of cocaine, while large brushstrokes align with his heroin use.
Kunst Halle Sankt Gallen, Gunnar Meier
Operating out of Zurich and London, art collective !Mediengruppe Bitnik hit headlines in 2014 with "Random Darknet Shopper", a computer program built given bitcoin purchasing power and free reign to buy items from the dark web and have them delivered to Kunst Halle gallery in St Gallen, Switzerland. The shopping bot, stationed within the exhibition space, bought cigarettes and master keys with its $100 weekly allowance, before deciding to throw a party with 10 ecstasy pills. Bought from Germany for $48 and concealed in a DVD case, they were nonetheless put on display.
Courtesy !Mediengruppe Bitnik
"The motivation for the artwork really came in the light of the Snowden revelations," says collective co-founder Carmen Weisskopf. "For internet artists it meant we had to re-evaluate the networks we work in. We became really interested in looking at these anonymous and encrypted networks from an artistic point of view."
Fred Tomaselli / Courtesy ofJames Cohan, New York, NY
American artist Tomaselli is a master of collage, weaving pills into his works of acrylic paint and resin. Embedding medication into his work -- "chemical cocktails" as the artist dubs them -- Tomaselli says "[they] can no longer reach the brain through the bloodstream and must take a different route to altering perception. In my work, they travel to the brain through the eyes." In "Dead Eyed Bird Blast" (1997) pills can be seen in the white dots between the fauna. An avid bird-watcher, Tomaselli has drawn a link between the two, describing ornithology as "witnessing a parallel universe." ("Dead Eyed Bird Blast" and other works by Fred Tomaselli are currently on display at the Toledo Museum of Art.)
New York Review Books
Born in Belgium, 1899, poet and painter Michaux was a teetotaller until mescaline came calling. His writings and drawings in "Miserable Miracle" (1957), an account of his experiments, details the mind expanding and fine motor skill inhibiting effects of the hallucinogen. His drawings show rhythmic scribbles and stippling in fluid -- albeit abstract -- forms, without an obvious subject. Film maker Eric Duvivier adapted Michaux's books in "Images Du Monde Visionnaire", a film attempting to conjure the imagery of Michaux's high. Michaux was unimpressed however, saying to try and recreate the psychedelic experience was "to attempt the impossible."
courtesy Van Gogh Museum, Amsterdam (Vincent van Gogh Foundation)
Why did Van Gogh use so much yellow in his painting? It's well known that the Dutch post-impressionist was partial to absinthe, excessive consumption of which may cause a yellow hue in vision. But clinical professor of pathology Paul Wolf argues that the volume required for this sort of effect is so vast as to be discounted. However, Wolf suggests overmedication of digitalis-- potentially prescribed for Van Gogh's medication -- would give the world a yellow-green tint. Indeed, in one portrait of Van Gogh's physician Paul-Ferdinand Gachet, he can be seen holding a stem of a purple foxglove -- from which digitalis is extracted -- in his hand. Other publications, however, claim that he was not treated with digitalis at all.
Cafe Slavia
Czech painter and illustrator Oliva was primarily a graphic artist, but his most famous work is a painting that hangs in Café Slavia, one of his favourite haunts, to this day. Called "Absinthe Drinker", the painting depicts a man accompanied by the Green Fairy, a manifestation of absinthe and its intoxicating allure. The highly-alcoholic drink was popular in bohemian Paris in the late 19th and early 20th century, James Joyce, Ernest Hemingway and Vincent Van Gogh all supping on the green spirit.
CNN  — 

Art and drugs have been happy bedfellows since before recorded history. The dawn of man was soon followed by the birth of curious types, seeking to alter their mental state and express it in every which way they could: song, dance, rudimentary forms of painting and inscription.

From Native Americans and peyote to Ancient Egyptians and blue lotus, high societies have always been a global phenomenon.

After thousands of years you’d be forgiven for being blasé about the subject. But a certain mystique refuses to budge when we talk about drugs and art. So why are we still intrigued when the two collide?

Drugs as a creative burden

“There was a time when art, intoxication, religion and the sacred were all the same thing,” says Mike Jay, author of “High Society: Mind-altering Drugs in History and Culture”.

Jay rattles through Minoans in ancient Crete and their opium habits, South Americans and hallucinogens; lotus-eaters in Homer’s “The Odyssey” and stories of witchcraft – potions and shape-shifting and communion with the natural world.

Hulton Archive/Archive Photos/Getty Images
Thomas De Quincey (1785-1859)

But for a modern understanding of the relationship between art and drugs, writer Thomas De Quincey is pivotal, suggests Jay. Best known for his autobiographical account of 1821, “Confessions of an English Opium-Eater”, De Quincey pioneered the ‘drug confession’, a mode that set the tone for many artists since.

“[He’s] playing a slightly ironic game,” suggests Jay, “saying that to the common person [opium is] just a painkiller, but to people like me – an artist – it takes me to places you can’t even dream of or imagine.

GABRIEL BOUYS/AFP/AFP/Getty Images
A close up of the thousands of resin pills that make up Damien Hirst's "Standing Alone in the Precipice and Overlooking the Arctic Wastelands of Pure Terror" (1999-2000).

“The pleasure and the marvels are beyond your imagination. But so are the perils and the pains.”

De Quincey’s ambivalence – a sense of both pride and anguish towards the burden of creativity and drug consumption – is an image that has been cultivated by others and has carried great currency in the centuries that followed.

Contemporary artist Bryan Lewis Saunders is a fine example. Saunders has created over 10,000 daily self-portraits and rose to prominence for his drug-induced series “Under the Influence”. He lives a hermetic life in Johnson City, Tennessee, impoverished but refusing to sell his work or engage with the commercial art market. Saunders, when pushed, says he now considers his life a work of art.

Across the Atlantic, Damien Hirst commented in 2000 about how his appetite for drugs and alcohol turned him into a “babbling wreck” in the past. Around the time of those remarks he was crafting “Standing Alone in the Precipice and Overlooking the Arctic Wastelands of Pure Terror” (1999-2000), one of numerous pharmacological works stretching back to his time at Goldsmith’s College of Art, London.

“It didn’t come from any of the things that I had,” said Hirst of “Standing”, “it came from everything I had.”

Drugs as an experiment

Some artists have experimented with drugs in a clinical fashion, embracing the notion, as Jay puts it, that “drugs are not great for writing and drawing and physically doing work.”

In the 1930s German scientists were trying to use mescaline to map hallucinations and learn about the brain, says Jay. Artist and poet Henri Michaux was similarly recording his own mescaline consumption, but with drawings; chaotic, kinetic works of incredible detail that nonetheless display a dissolution of fine motor skills.

Marina Abramović went down a similar route with “Rhythm 2” (1974), ingesting in two stages medication for catatonia and then for schizophrenic behavior. At first Abramović experienced muscular convulsions, then under the second drug mental detachment, “forgetting who and where I am,” she recalled in “Marina Abramović: The Artist is Present”.

Jay describes how throughout the twentieth century “drug use was pathologized, marginalized and socially excluded.” Taking this to its local endpoint was Zurich/London art collective !Mediengruppe Bitnik.

In 2014 their installation “Random Darknet Shopper” brought drug experimentation into the digital age. Their creation was a bot, given a weekly allowance in bitcoins to purchase items from the dark web via TOR.

Items were picked at random and delivered to the Kunst Halle in St. Gallens, Switzerland. One day the bot decided to throw a party, when it bought 10 ecstasy pills concealed in a DVD case. Like the other items bought on the dark web, they went on display, contraband becoming an artistic expression, in and of itself.

Drugs as a medium

Other artists are more playful when it comes to drugs, riffing on perceptions and preconceptions of illicit substance use (and abuse).

Kenny Scharf’s “Closets”, a series of over 30 installations, started life in 1981 as a “safe space,” “a place to go and trip” on magic mushrooms, he explained in 1985. Explosions of Day-Glo phantasmagoria, Scharf’s “Closets” are as stimulating as they come.

courtesy Diddo
"Ecce Animal" (2013) by Diddo, sculpted from cocaine and gelatine.

Dutch artist Diddo sculpted “Ecce Animal” (2013), a skull made from street-sourced cocaine, testing its purity (a mere 15-20%) before combining it with gelatine.

A Yorick for Generation X, the artist explains the piece is not intended to be a “parable on the self-destructiveness of addiction or substance abuse,” as you might expect. Instead it’s intended to be a meditation on the conflict between civility and our animal instincts – a conflict resolved by the drug.

Sarah Schoenfeld
"Opium" (2013) by Sarah Schoenfeld, part of her series "All You Can Feel".

As a medium, we also see drugs in the work of Fred Tomaselli and Sarah Schoenfeld. Tomselli collages with pills and has drawn connections between with medically-induced states and the “parallel universe” of his unremarkable hobby, bird watching, two subjects he frequently combines. Schoenfeld meanwhile drops drug solutions onto film negatives, subverting the normal method of light exposure and, like a brain on drugs, allowing the film to “see” things that aren’t actually there.

The enduring appeal

Some artists have earned fortunes from their drug-inspired art; others notoriety. But as consumers, what’s its enduring appeal?

“It forms a bridge into a kind of demimonde,” suggests Jay. “I think on one level it’s as prosaic as that.”

“On another I think drugs are about raw, unmediated experience in a world that’s increasingly mediated. We live very safe lives, relatively speaking,” he says.

“I think we still have a sense that there’s something connected with drugs that can take us into realms, types of immediate experiences that are hard to come by in our mediated culture.”

It’s a conceit, of course. For most of the works detailed above – “Rhythm 2” a notable exception – our experience and interaction with them is mediated by the gallery environment, a safe space, like Scharf’s “Closets”, in which to reach into this illicit world.

You could go as far as to argue we consume this art almost for the same reason we consume drugs.

“You’re taking a drug for a new experience,” says Jay. “It could be fantastic or it could be terrible – but it’s going to feel real.”